?:definition
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unique, genetically controlled determinants present on antibodies whose specificity is limited to a single group of proteins such as another antibody molecule or an individual myeloma protein; the idiotype appears to represent the antigenicity of the antigen binding site of the antibody and to be genetically codetermined with it; the idiotypic determinants have been precisely located to the immunoglobulin variable region of both immunoglobin polypeptide chains.
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