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any of the accumulations of lymphoid tissue organized as definite lymphoid organs, varying from 1 to 25 mm in diameter situated along the course of lymphatic vessels and consisting of an outer cortical and an inner medullary part; the main source of lymphocytes of the peripheral blood and, as part of the reticuloendothelial system, serves as a defense mechanism by removing noxious agents, such as bacteria and toxins.
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