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  • common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death; histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa; the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system.
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