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  • A tyrosine derivative with a nitro group attached to carbon 3 on the phenyl ring that is a product of tyrosine nitration mediated by reactive nitrogen species, including peroxynitrite anion and nitrogen dioxide. 3-nitrotyrosine is a biomarker of cell damage, inflammation, and NO (nitric oxide) production; it is overproduced in many diseases where oxidative stress plays a key role.
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