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  • Specifika hydroximetylglutaryl-CoA-reduktaser som utnyttjar kofaktor NADP. Reaktionen är: (R)-mevalonat + CoA + 2 NADP+ = (S)-3-hydroxi-3-metylglutaryl-CoA + 2 NADPH + 2 H+. Leverenzymer tillhörande denna klass ingår i biosyntesen av kolesterol. EC 1.1.1.34.
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