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  • A formulation composed of the local anesthetic lidocaine and the vasoprotective agent tribenoside that can be used for the treatment of hemorrhoids. Upon rectal administration of the lidocaine mixture with tribenoside, lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses. This causes local anesthesia and relieves pain. Tribenoside may exert anti-inflammatory, mild analgesic, wound-healing, fibrinolysis-promoting, membrane-stabilizing and venotropic properties. This may relieve pain, halt inflammation, protect blood vessels, and may help repair and heal wounds.
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