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  • A heterogeneous group of congenital spinal anomalies that result from defective closure of the neural tube early in fetal life. [HPO:probinson]
  • Incomplete closure of the embryonic neural tube, whereby some vertebral arches remain unfused and open. The mildest form is spina bifida occulta, followed by meningocele and meningomyelocele. [HPO:probinson]
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