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  • A synthetic quaternary ammonium base derivative, parasympathomimetic bethanechol is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Generally used to increase smooth muscle tone, bethanechol is used to treat reflux esophagitis and to initiate urination after surgery, in urinary infections, or for enlarged prostate. It may cause hypotension, cardiac rate changes, and bronchial spasms. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C28866\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C28866\' NCI Thesaurus)
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