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  • A polycyclic aromatic hydrocarbon and metabolite of benzo(a)pyrene with potent cytotoxic and mutagenic properties. Benzo(a)pyrene-trans-7,8-dihydrodiol is an intermediate in the conversion of benzo(a)pyrene to the highly potent mutagen and carcinogen benzopyrene diol epoxide via cytochrome P450 CYP1A1.
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