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  • Grafts obtained from a donor or produced artificially (i.e., synthetic) that are intended to replace an area of diseased or injured skin. Skin grafts used in humans may be of biological origin, obtained mainly from the body of the same person (i.e., autograft), from another person (i.e., allograft, typically from cadavers), and less frequently, from a different species (i.e., xenografts); synthetic polymeric membranes (e.g., hydrogels); or a combination of natural and synthetic materials (i.e., composite grafts), including living elements and synthetic materials developed using bioengineering techniques (i.e., bioartificial). Skin grafts are used in the healing of extensive skin losses, including large wounds and burns. Biological autografts and some bioengineered products are intended for use as permanent implants, while other skin grafts must be removed after a few days.
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