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  • Instruments designed with a blade that is appropriate for cutting objects, tissues, and other anatomic structures. These devices typically consist of manual, handheld instruments including a proximal handle and a distal blade with one or more sharp edges. Knives are available in a variety of shapes and sizes and these may vary depending on their intended purpose. Dedicated knives are used in surgical (e.g., ophthalmic, orthopedic, middle ear, plastic), dental (e.g., periodontic, prosthodontic), biopsy (e.g., uterine) and postmortem (e.g., autopsy) procedures. Some knives may be also intended to cut specific materials (e.g., paraffin). Small knives known as scalpels that are designed for easy cutting or dissection of soft tissue are also available.
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