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  • Microscopes designed to magnify an image using an electron beam instead of light, which allows greater magnification (500,000x is typical) and resolution than a light microscope. The images are usually observed on a fluorescent screen or through photographs. There are two basic types of electron microscopes: the transmission electron microscope (TEM), which basically operates like a light microscope but uses an electron beam, and scanning electron microscopes (SEM), which provide a three-dimensional image of the surface of the examined object; some electron microscopes combine both techniques. TEMs intended for clinical use permit highly detailed visualization of tissue, individual cells, and cell structures; SEMs are intended mainly for research and, less frequently, for clinical applications.
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