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  • Microtomes contained in a temperature-controlled stainless steel cabinet called a cryostat. The cryostat microtome allows microtomists to section frozen tissue specimens for histopathologic analysis. The microtome, tissue specimen, and knife are housed in a thermostatically controlled chamber insulated with polyurethane foam. The operator passes the specimen through an opening in the chamber and places it on a refrigerated holder near the microtome. The microtome freezes the specimen with an aerosol-propelled freezing agent before placing it in the chamber or inserts it into an optional quick-freezing specimen holder or polyglycol matrix.
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