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  • Electron microscopy reagents used to provide better contrast (e.g., by artificial coloration) to the constituent parts of the cells and the intercellular material when magnifying an image using an electron beam instead of light. These stain reagents typically consist of positive heavy metal particles (e.g., gold) or substances that attach around the specimen, rather than to the specimen itself (i.e., negative stains) or by any other mean facilitating the differentiation of the cell and/or tissue constituents or products. Electron microscopy stains are used in cytology and histology to identify and classify human cells, microorganisms (e.g., bacteria, virus, fungi), and in other in-vitro clinical tests and/or for research.
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