?:definition
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Increased size of cerebral gyri, often associated with a moderate reduction in the number of sulci of the cerebrum. [HPO:probinson]
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Pachygyria is a malformation of cortical development with abnormally wide gyri with sulci 1,5-3 cm apart and abnormally thick cortex measuring more than 5 mm (radiological definition). See also neuropathological definitions for 2-, 3-, and 4-layered lissencephaly. [COST:neuromig, HPO:probinson, PMID:22427329]
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