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Stage II includes: IIA (T3, N0, M0); IIB (T4, N0, M0). T3: Tumor invades through the muscularis propria or into non-peritonealized pericolic or perirectal tissues. T4: Tumor directly invades other organs or structures, and/or perforates visceral peritoneum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th ed.)
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