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  • A primary or metastatic malignant neoplasm affecting the bones. Representative examples of primary malignant bone neoplasms include osteosarcoma, chondrosarcoma, and Ewing sarcoma. Primary malignant bone neoplasms most often affect children and adolescents. Representative examples of metastatic malignant neoplasms to the bones include carcinomas arising from other anatomic sites and lymphomas. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C4016\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C4016\' NCI Thesaurus)
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