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  • This is a rare malignant neoplasm of the soft tissue. It is typically a disease of children and young adults. It is characterized by t(11:22) (q24: q12) resulting in the expression of EWS/FLI-1 chimeric transcript. Most commonly occurs in the paravertebral region, chest wall, pelvis and lower extremities. Treatment includes local excision with consideration for post operative chemotherapy and/or radiotherapy. - 2003 Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C7135\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C7135\' NCI Thesaurus)
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