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  • Germicides intended for use in liquid-phase for killing and/or total inactivation of many microorganisms (e.g., viruses, bacteria, fungi). These germicides typically consist of a non-corrosive chemical solution used in disinfecting or sterilizing units that include a closed chamber in which the time, temperature, and/or concentration of the germicide during the sterilization (typically by immersion) process are controlled. Liquid germicides usually require high concentrations, elevated temperatures, and several hours of exposure time for sterilization purposes. Therefore, they are mainly used for disinfection rather than for sterilization purposes. Liquid germicides are used mainly to disinfect medical devices and supplies that cannot be heat-sterilized due to their sensitivity to high temperatures (e.g., devices including plastic and/or rubber components). The most frequently used liquid germicides are glutaraldehyde, hydrogen peroxide, and ortho-phthalaldehyde.
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