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  • An autosomal dominant hereditary neoplastic syndrome. Mutations in the SMAD4 or BMPR1A genes have been identified in the majority of patients. It is characterized by the presence of multiple juvenile polyps in the gastrointestinal tract. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C7754\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C7754\' NCI Thesaurus)
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