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  • A B-cell non-Hodgkin lymphoma composed of small lymphocytes which surround and replace the splenic white pulp germinal centers. It involves the spleen and splenic hilar lymph nodes, bone marrow, and often the peripheral blood. Patients present with splenomegaly and the clinical course is indolent. (WHO, 2001) Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C4663\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C4663\' NCI Thesaurus)
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