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  • A regimen consisting of cyclophosphamide, vincristine, doxorubicin and high-dose methotrexate used to treat aggressive forms of non-Hodgkin lymphoma; also used as primary treatment of AIDS-related and low-risk Burkitt\'s lymphoma. Intrathecal cytarabine and methotrexate are included in this regimen as either prophylaxis or treatment of central nervous system (CNS) disease.
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