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  • Radiographic contrast media containing iodine. Iodinated radiographic contrast media may be ionic or non-ionic depending on whether the contrast agent dissociates into ionic particles in solution or exists as a stable polar molecule in solution, respectively. Most iodinated radiographic contrast media is based on molecules containing benzene rings to which three iodine atoms have been attached (i.e., a tri-iodinated benzene ring). Tri-iodinated benzene ring-containing contrast media may be referred to as a monomer or a dimer depending on whether it incorporates one or two benzene rings in its structure. Iodinated radiographic contrast media are typically used intravenously/intra-arterially; however, they may also be administered orally/rectally, by inhalation, or injected into the genitourinary tract or intrathecally.
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