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  • Encoded by Chemokine Receptor Genes (GPCR Family), cell surface Chemokine Receptors are seven-transmembrane G protein-coupled receptor glycoproteins that bind to chemokines and mediate the migration of pro-inflammatory cells. Like chemokines, the chemokine receptors can be divided, according to variations in a shared cysteine motif, into at least three structural branches: CR, CCR, and CXCR. (NCI)
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