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  • Glicoproteína plasmática endógena de 105 KDa produzida principalmente pelo FÍGADO e em MONÓCITOS. Inibe um amplo espectro de proteases, inclusive as proteases do COMPLEMENTO C1R e do COMPLEMENTO C1S da VIA CLÁSSICA DO COMPLEMENTO, e as SERINA PROTEASES ASSOCIADAS À PROTEÍNA DE LIGAÇÃO A MANOSE. Indivíduos deficientes em C1-INH sofrem de ANGIOEDEMA HEREDITÁRIO TIPOS I E II.
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