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  • Stage Group III is subdivided into IIIA (T1-2, N1, M0), IIIB (T3-4, N1, M0) or IIIC (any T, N2 M0). T1: Tumor invades the submucosa. T2: Tumor invades muscularis propria. T3: Tumor invades through the muscularis propria into the subserosa or into non-peritonealized pericolic or perirectal tissues. T4: Tumor directly invades other organs or structures, and/or perforates visceral peritoneum. N1: Metastasis in 1 to 3 regional lymph nodes N2: Metastasis in 4 or more regional lymph nodes. M0: No distant metastasis. (AJCC 6th ed.)
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