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  • A mixture of the sodium salts of the sulfate esters of estrogen including sodium estrone sulfate, sodium equilin sulfate and the concomitant component, 17 alpha-estradiol, that is used for estrogen replacement. Estrogens bind to nuclear receptors in estrogen-responsive tissues and modulate the secretion of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), stimulate skeletal growth, and have a widespread effect on metabolic processes including protein transport and electrolyte balance.
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