?:definition
|
-
The sodium salt of a low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin\'s mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C75769\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C75769\' NCI Thesaurus)
|