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Point-of-care breath analyzers used to determine the increase in carbon isotope content (e.g., carbon-13) in a breath sample, usually expressed as a carbon isotope relation, such as the relation of carbon-13 to carbon-12, after administration of carbon-13-labeled substrates. These analyzers typically use gas chromatography techniques. Carbon isotope breath analyzers are used to assess bacterial overgrowth and colonization in gastroenterology (e.g., determination of urea in breath for detection of Helicobacter pylori), to measure organ function, and to evaluate digestion and absorption of carbohydrates, lipids, and proteins.
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