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  • Stage IV is divided into stages IVA and IVB. In stage IVA, most of the skin is reddened, and any amount of the skin is covered with patches and/or plaques (areas of abnormal tissue) or tumors (lumps of malignant cells). Cancer has spread to lymph nodes, and the lymph nodes may be enlarged. In stage IVB, most of the skin is reddened, and any amount of the skin is covered with lesions or tumors. Cancer has spread to other organs in the body. Lymph nodes may be enlarged and cancer may have spread to them. Stage IV may also be classified based on how many abnormal lymphocytes (white blood cells) are found in the blood.
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