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  • A synthetic prodrug of ganciclovir, a nucleoside analogue of 2\'-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA polymerase, viral DNA synthesis, and viral replication. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2629\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2629\' NCI Thesaurus)
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