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  • The inactivation of gene expression by a posttranscriptional mechanism. [GOC:mah, PMID:15020054]
  • The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation (\'silencing\') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. [GOC:ems, PMID:11201747, PMID:11713190, PMID:18771919]
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