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  • Catalysis of the reaction: CoA + substrate-serine = adenosine 3\',5\'-bisphosphate + substrate-serine-4\'-phosphopantetheine. The transfer of the 4\'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form. [EC:2.7.8.7, PMID:10320345, PMID:11867633, PMID:8939709]
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