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  • The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules (\'de novo\' microtubule formation). [GOC:go_curators, ISBN:0815316194, PMID:12517712]
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