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  • Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans. [GOC:jl, GOC:mr, PMID:11102361, PMID:20622855, Wikipedia:XY_sex-determination_system]
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