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  • The sum of the primary and secondary Gleason scores. If three patterns are identified, it is the sum of the primary pattern score and the score of the least well-differentiated pattern. (Gleason, D. F. (1977). The Veteran\'s Administration Cooperative Urologic Research Group: histologic grading and clinical staging of prostatic carcinoma. In Tannenbaum, M. Urologic Pathology: The Prostate. Philadelphia: Lea and Febiger. pp. 171-198.)
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