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?:definition
  • Solid preparation consisting of granules showing a rate and/or place of release different from that of conventional-release granules. This deliberate modification is achieved by a special formulation design and/or manufacturing method. Modified-release granules are usually single-dose preparations intended for oral use, and include prolonged-release, delayed release and pulsatile-release granules. The generic term \'modified-release granules\' is used only when the more specific terms \'gastro-resistant granules\' or \'prolonged-release granules\' do not apply.
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