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Cabinets designed as a partial or total containment enclosure for safe manipulation of moderate and/or high-risk microorganisms and other biological hazardous materials (i.e., they offer biological safety). These cabinets typically produce a vertical laminar flow; they are available in three general types (class I, II, and III) according to their performance characteristics and applications. Class I cabinets protect the operator and the environment but not the product; class II cabinets protect the operator, the product, and the environment; and class III cabinets offer the maximum degree of protection to the product, operator, and environment. Biological safety cabinets are used for handling of cell cultures and human pathogens (e.g., bacteria, virus, parasites) and other biohazardous materials, extreme toxic agents (e.g., chemotherapy drugs), and also for tissue culture and tumor virus work.
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