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  • Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+. [EC:1.3.1.48, KEGG_REACTION:R04556, KEGG_REACTION:R04557, MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN]
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