PropertyValue
?:definition
  • Human G(i) Alpha Proteins (G-Alpha 1 Family) are 40-kDa guanine nucleotide-binding alpha protein subunits of heterotrimeric G protein transducers (alpha, beta, gamma) in transmembrane signaling systems involved in hormonal regulation of adenylate cyclase. Containing virtually identical/similar beta and gamma chains, G proteins are most distinguished by alpha chains. G(i) proteins (alpha(i) subunit) inhibit cyclase in response to beta-adrenergic stimuli. Specific alpha chain regions appear to interact with guanine nucleotides, receptors, effector enzymes, and G protein beta-gamma complex. G proteins that inhibit adenylate kinase and regulate other plasma membrane enzymes are substrates for pertussis toxin. (NCI)
?:hasCUIAnnotation
?:hasGeneratedBy
?:type

Metadata

Anon_0  
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/net/provenance/ns#DataItem>
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/03/trix/rdfg-1/Graph>
<http://xmlns.com/foaf/0.1/primaryTopic> <https://research.tib.eu/covid-19/entity/C1333649_NCI>
<http://xmlns.com/foaf/0.1/topic> Anon_0
<http://www.ontologydesignpatterns.org/cp/owl/informationrealization.owl#realizes> <https://research.tib.eu/covid-19/data/entity/C1333649_NCI>
<http://purl.org/net/provenance/ns#createdBy>
Anon_1   (more)
expand all