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?:definition
  • A high grade intraepithelial neoplasia in which there is marked architectural distortion and crowding of the glands, associated with severe cellular atypia. The neoplastic cells display pleomorphic and hyperchromatic nuclei.
  • This lesion shows moderate or marked architectural distortion with glandular crowding and prominent cellular atypia. It includes moderate dysplasia and severe dysplasia. (WHO, 2000)
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