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  • Proteinase Inhibitor Genes encode Proteinase Inhibitor Proteins that block the activity of proteases, endopeptidases that catalyze the cleavage of internal peptide bonds in a polypeptide or protein substrate (Serine Endopeptidases, Cysteine Endopeptidases, Aspartic Endopeptidases, Metalloendopeptidases, and other Endopeptidases). (NCI)
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