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Stage IVA includes: T4, any N, M0. T4: tumor invades bladder mucosa and/or bowel mucosa (bullous edema is not sufficient to classify a tumor as T4). M0: no distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.) Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C6309\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C6309\' NCI Thesaurus)
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