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  • Enzima do tipo citocromo P450 hidroxilase de microssomos hepáticos que oxida um amplo espectro de substratos inclusive ESTEROIDES, ÁCIDOS GRAXOS e XENOBIÓTICOS. Exemplos de substratos farmacêuticos para CYP2C8 incluem PACLITAXEL, torasemida e AMODIAQUINA.
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