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Hematology analyzers designed to measure total blood and/or some of its components (e.g., plasma and red cell) volume in a person\'s circulatory system; the devices can also determine the normal quantity of blood that an individual should have according to his/her body size. The measurements are based on the time rate of disappearance of a radioactive tracer (e.g., iodine isotope 131, I131) that is typically attached to albumin (the most abundant blood protein). A small amount of tracer is injected through an intravenous line using a special, pre-filled, small, and calibrated syringe. Typically five samples are collected using a standard blood collection setup in five- to six-minute intervals after an initial waiting period of 10 to 12 minutes. Blood/component volume measuring analyzers are intended for use after sudden blood loss (e.g., hemorrhage, surgery); they may be used also for blood donors and in patients suffering from renal and/or heart failures.
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