PropertyValue
?:definition
  • An extrachromosomal circular DNA located in the nucleus that is relatively small in size and contains chromatin but lacks a centromere and telomeres. These circular DNAs are found in tumor cells and are able to replicate during cell division during chromosome replication. They often contain extra copies of oncogenes and/or genes involved in drug resistance and lack transcription regulatory elements. Unregulated expression of genes present in these structures may play a role in tumor growth and tumor cell survival.
?:hasCUIAnnotation
?:hasGeneratedBy
?:type

Metadata

Anon_0  
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/net/provenance/ns#DataItem>
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/03/trix/rdfg-1/Graph>
<http://xmlns.com/foaf/0.1/primaryTopic> <https://research.tib.eu/covid-19/entity/C1512047_NCI>
<http://xmlns.com/foaf/0.1/topic> Anon_0
<http://www.ontologydesignpatterns.org/cp/owl/informationrealization.owl#realizes> <https://research.tib.eu/covid-19/data/entity/C1512047_NCI>
<http://purl.org/net/provenance/ns#createdBy>
Anon_1   (more)
expand all