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  • The presence of genomic instability associated with defective DNA mismatch repair in greater than 30% of the microsatellite instability (MSI) biomarkers in a tumor sample. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C36493\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C36493\' NCI Thesaurus)
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