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The Ig constant chain domains and a single extracellular domain in each type of MHC chains are homologous and approximately 100 amino acids long, and include a conserved intra-domain disulfide bond. Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions. This subfamily is the C-2-type and includes glycoproteins and other unrelated proteins with immunoglobulin domains eg. carcinoembryonic antigens and fibroblast growth factor receptors. (InterPro IPR003598)
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