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  • An Epstein-Barr negative disorder with a nonprogressive clinical course affecting predominantly adults and characterised by the proliferation of large granular lymphocytes with natural killer cell immunophenotype. The T-cell receptor genes are not rearranged and it is not clear whether this disorder is reactive or neoplastic. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C39591\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C39591\' NCI Thesaurus)
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