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A recombinant monoclonal antibody directed against the human suppressor-cytotoxic T-cell subset and designed to deplete circulating Leu 2A-positive lymphocytes. The antigen LEU 2A, also known as CD8, is present on a subset of natural killer (NK) lymphocytes as well as the on the human suppressor/cytotoxic T-lymphocyte subset. (NCI04)
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